Pexophagy

Pexophagy Inducer

Peroxisome
dysfunction in disease

• X-linked adrenoleukodystrophy
• Skeletal abnormalities
• Alzheimer’s disease
• Neonatal hypotonia
• Bile Acid Synthesis Defect
• Cancer
• Diabetes

Pexophagy inducer screening for various library

• Global first target & M.O.A
• Novel target I.D
• 1st in class : First I.D Mecham.
• Autophagy (2020), BBRC (2021)

• 펙소파지 모니터링 플랫폼 (HeLa/mCherry-Hluorin-PTS1 세포주)에서 pexophagy inducer 처리에 따른 펙소파지 증가